Journal of Pharmaceutical Research International

Dementia is a progressive neurodegenerative disease that significantly affects patients, caregivers, and health systems worldwide. Collaborative care models (CCMs) have emerged as promising strategies that integrate multidisciplinary interventions to improve patient outcomes and reduce caregiver burden. This review systematically evaluated randomized controlled trials, cohort studies, and cluster-randomized trials from 2010 to 2023. A total of 315 articles were screened, and 15 met the inclusion criteria. These included 10 randomized controlled trials and 5 observational studies. Case reports, editorials, and non-English publications were excluded. Findings demonstrate that CCMs improve quality-adjusted life years, reduce behavioral symptoms, and delay institutionalization, with some models showing reductions in caregiver strain and healthcare utilization. Remote care programs, such as the Care Ecosystem, highlight how technology can extend access to underserved populations. However, results across studies are heterogeneous, with some interventions demonstrating limited improvements in quality of life or caregiver burden. Implementation feasibility varies across healthcare systems, and barriers include resource limitations, workforce turnover, and integration challenges. Cost-effectiveness analyses suggest CCMs can save healthcare costs, particularly when targeted to patients living at home. Despite promising results, significant gaps remain, including inconsistent outcome measures, limited evidence from diverse populations, and insufficient long-term follow-up. Tailored, scalable models incorporating evidence-based practices and technology offer the most promise. Addressing disparities and ensuring sustainability will be critical for advancing dementia care globally. This review emphasizes the urgent need for further research to optimize program design, improve equity, and standardize outcome reporting.

Objective: To evaluate the efficacy, cost-effectiveness and impact of collaborative care models on the outcomes of dementia care provided to both patients and their caregivers. This review will also aim to outline areas in which further research is necessary to promote better care delivery and scalability.

Methods: A systematic review of the literature was conducted, focusing on studies published between 2010 and 2023. The review included randomized controlled trials, cohort studies, and cluster-randomized trials examining the outcomes of CCMs in dementia care. Studies were selected based on their focus on patient quality of life, caregiver burden, behavioral symptom management, healthcare utilization, and cost-effectiveness.

Findings: The evidence suggests that CCMs improve dementia care outcomes through tailored interventions addressing medical, emotional, and social needs. Studies demonstrated significant improvements in patient quality-adjusted life years (QALYs), reductions in behavioral symptoms, delayed institutionalization, and cost savings. While some interventions reduced caregiver burden and hospitalizations, others failed to significantly address unmet needs or patient quality of life, signifying the influence of program design, healthcare settings, and population characteristics.

Conclusion: Collaborative care models offer a practical approach to progressing dementia care, tending to the double needs of patients and caregivers. Tailored interventions that involve multidisciplinary teams, evidence-based practices, and technology hold promise for wide-ranging application. However, further research is required to optimize program design, ensure scalability, and address disparities in access and outcomes. Bridging these gaps will enhance the effectiveness of CCMs and contribute to better dementia care globally.