Frequency of Ventricular Septal Rupture in Patients of Acute Myocardial Infarction
Aijaz Ali
Cardiac Imaging, National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Vashu Mal
Interventional Cardiology, National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Rameez Ahmed
Interventional Cardiology, National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Farhan Memon
Interventional Cardiology, National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
. Lalchand
Cardiac Imaging, National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Muhammad Faizan
Interventional Cardiology, National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Naveed Ahmed Shaikh
Interventional Cardiology, National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Muhammad Yasir
Cardiology, Liaquat University of Medical and Health Sciences (LUMHS), Jamshoro, Pakistan.
Muhammad Tariq
Cardiology, National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
*Author to whom correspondence should be addressed.
Abstract
Objective: To determine the frequency of ventricular septal rupture in patients of acute myocardial infarction presented at the adult cardiology department of National Institute of Cardiovascular Disease (NICVD), Karachi.
Methods: A cross-sectional study was conducted at the National Institute of Cardiovascular Disease, Karachi, Pakistan for a period of six months. A total of 384 patients with acute myocardial Infarction diagnosed within 4 weeks duration were included in this study. ECG and transthoracic echocardiogram (TTE) was formed. Patients were followed for 7 days and the study outcome. Data was collected on a pre-designed structured questionnaire.
Results: The average age of the patients was 54.40±7.99 years. Frequency of ventricular septal rupture in patients of acute myocardial infarction was observed in 1.3% (5/384) in which defect in Inter ventricular septum was observed in 60%, Evidence of left-to-right shunt 40%.
Conclusion: Our study revealed a ventricular septal rupture (VSR) rate of 1.3%. The study further revealed a correlation between smoking and rate of VSR.A multidisciplinary team of researchers must work together to develop a plan that is specific to each patient.
Keywords: Ventricular septal rupture, acute myocardial infarction, transthoracic echocardiogram