Theranostics Usage of Nano Drug Complexes in Clinical Patientcare
Taha Nazir *
Advanced Multiple Inc., 6660 Kennedy Rd Mississauga ON, L5T2M9, Canada.
Saeed Ur Rashid Nazir
Faculty of Pharmacy, College of Pharmacy, University of Sargodha, Sargodha 40100, Pakistan.
Humayun Riaz
Rashid Latif Collegr of Pharmacy, Rashid Latif Khan University, Lahore, Pakistan.
Pervaiz Akhtar Shah
Punjab University College of Pharmacy, University of the Punjab, Lower Mall, Lahore, Pakistan.
Misbah Sultana
Punjab University College of Pharmacy, University of the Punjab, Lower Mall, Lahore, Pakistan.
Safia Sultana Munir
Shalamar Medical and Dental College, Lahore, Pakistan.
. Ubaidullah
Department of Community Medicine, Swat Medical College, Marghazar Road, Kukrai, Saidu Sharif Swat, KPK, Pakistan.
Marwa M. Elmaghrabi
Department of Microbiology, Faculty of Science, King Saud University, P.O.Box 51178, Riyadh 11543, Saudi Arabia and Center of Excellence for Research in Regenerative Medicine and Applications, Faculty of Medicine, Alexandria University, Egypt.
Umer Farooq
Eye Bank, Al-Shifa Trust Eye Hospital, GT Road, Rawalpindi, Punjab, Pakistan.
Ishtiaq Rabi
Advanced Multiple Inc., 6660 Kennedy Rd Mississauga ON, L5T2M9, Canada.
Nida Taha
Advanced Multiple Inc., 6660 Kennedy Rd Mississauga ON, L5T2M9, Canada.
*Author to whom correspondence should be addressed.
Abstract
The extraordinary expansion in the nanomedicine with the development of new nano drug particles made surprising advancement in diagnosis and treatment. Nano drug complexes have amazing medicinal properties and clinical benefits in health care practice. That allows these to attach, absorb and deliver the nano molecule including RNA, DNA, probes and proteins at desired site in an efficient manner. Certain diagnostic agents are potential used to theranostics purpose in nano drug’s formulation. Additionally the biotransformation technique used to achieve the desired clinical results and/ or pharmacological benefits. The reproducible synthesis of monodispersed nano drug particles play efficient role in healthcare system. Thus, we aimed this study to review the theranostics usage of nano drug complexes in clinical patientcare. The current scientific information used in nano drug particles; non-invasive imaging techniques; and enhanced permeability and retention are tried to incorporate to enhance the credibility of this review article. The medicinal potential of nano drug complexes can effectively be used with the interventions of modern technologies, image guided drug delivery system, antigen targeted immunotherapy and radio-guided drug distribution for individualized and poly-pharmacy practice.
Keywords: Theranostics, nano drug complexes, clinical patientcare, nanoparticles, chemotherapy, targeted drug delivery