Anti-Fungal efficacy of Probiotics in Heat Cure Dentures Base Resin: An In-vitro Study
R. Kirupa Shankar *
Department of Prosthodontics and Crown & Bridge, Sri Ramachandra Faculty of Dental Sciences, SRIHER, Chennai, Tamil Nadu, India.
Hemamalini Balaji
Department of Prosthodontics and Crown & Bridge, Sri Ramachandra Faculty of Dental Sciences, SRIHER, Chennai, Tamil Nadu, India.
N. Shanmuganathan
Department of Prosthodontics and Crown & Bridge, Sri Ramachandra Faculty of Dental Sciences, SRIHER, Chennai, Tamil Nadu, India.
N. Parthasarathy
Department of Prosthodontics and Crown & Bridge, Sri Ramachandra Faculty of Dental Sciences, SRIHER, Chennai, Tamil Nadu, India.
I. Athiban
Department of Prosthodontics and Crown & Bridge, Sri Ramachandra Faculty of Dental Sciences, SRIHER, Chennai, Tamil Nadu, India.
R. Thirumalaikumaran
Department of Pharmacology, School of Pharmacy, Sathyabama Institute of Science and Technology, Jeppiar Nagar, Semmenchery, Chennai, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
Aim: To assess if probiotics alter the adherence of candida species onto the denture base material made with Polymethylmethaacrylate(PMMA).
Materials and Methods: Sample number of 10 per denture base resin with Sample dimensions of length 10 mm × 10 mm and width 2 mm.
Test Group: PMMA samples coated with probiotics at varying concentrations dipped in saliva Containing candida species.
Control Group: PMMA samples in saliva containing candidal species without probiotics.
Results: Significant difference of candida cell count on PMMA was evident before and after giving probiotic. On the heat cure denture base materials, there was a significant decrease in Candidal cell counts when the probiotic concentrations (2.5, 5, 10, 15 and 20 µg/ml) increased.
Keywords: Oral cavity, dentures, PMMA, candida infection, prophylaxis