Correlation of Serum Urate Levels and Lichen Planus in Male and Female Patients
Hira Mughal
Bilawal Medical College, Jamshoro, Pakistan and Department of Dermatology, PUMHSW, Nawabshah, Pakistan.
Shazia Bano
Department of Dermatology, PUMHSW, Nawabshah, Pakistan.
Hafiz Bashir Ahmed Kalhoro
Department of Dermatology, LUMHS, Jamshoro, Pakistan.
Munazzah Meraj *
Department of Biochemistry, IPRS, PUMHS, Pakistan.
Zonish Khalid
WMO, Liaquat University Hospital, Hyderabad, Pakistan.
Sabira Baz Khan
WMO, District Health Office, Hyderabad, Pakistan.
*Author to whom correspondence should be addressed.
Abstract
Aim: To correlate serum urate level in male and female patients with lichen planus (LP) presenting at Dermatology department, Liaquat University Hospital Jamshoro.
Methodology: This Cross-sectional study was conducted from 2019 to 2020.Total 126 patients, divided into two equal groups male(n=63) and female (n=63), between the age of 20-50 years and duration of disease from one month after eruption of lesion to 18 months were incorporated in this study. The patients having gout, obesity, chronic kidney disease, Pregnant ladies, smoker and those taking serum urate lowering drugs or steroids were excluded from this study. After taking history with clinical examination, patients were subject to height, weight, BMI, and duration of disease in months was stated.
Results: Total 126 patients with age range between 20-50 years and the mean age was 32.5 ± 4.47 years in male and 35.3±6.74 years in females were analyzed. The mean BMI was 23.6 ± 2.68 kg/m2 in male and 22.5 ± 3.47 in kg/m2 females were recorded. The mean duration of disease was 35.4 ± 16.92 and 37.12 ± 18.92 weeks were recorded in male and female respectively. The mean serum urate level in Idiopathic Lichen Planus patients was 3.82 ± 0.79 mg/dL in male and 2.3+0.43 mg/dL in female were observed.
Conclusion: Our study results indicate that there is a positive correlation between LP and serum serum urate levels in male and female patients.
Keywords: Serum uric acid, lichen planus, BMI