A Review on Transdermal Drug Delivery Patches
R. Sanjai Kumar
Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels Institution of Science, Technology and Advanced Studies, Pallavaram, Chennai-600117, Tamilnadu, India.
D. Akila Devi *
Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels Institution of Science, Technology and Advanced Studies, Pallavaram, Chennai-600117, Tamilnadu, India.
N. Gokul Raj
Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels Institution of Science, Technology and Advanced Studies, Pallavaram, Chennai-600117, Tamilnadu, India.
M. Deepa
Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels Institution of Science, Technology and Advanced Studies, Pallavaram, Chennai-600117, Tamilnadu, India.
*Author to whom correspondence should be addressed.
Abstract
Human civilizations have used substances to the skin as cosmetic and therapeutic agents for thousands of years. The skin, on the other hand, was not exploited as a drug delivery method until the twentieth century. The term “transdermal” was first used in 1944 by Merriam Webster, indicating that it is a relatively new notion in medicinal and pharmacological practice. Transdermal medicines are doses that are self-contained and distinct. To produce a systemic effect, drugs are delivered through the skin. Without causing any changes in the drug’s plasma concentration Topical application of medicinal medicines has a number of advantages. There are numerous advantages to this technique of drug delivery over traditional oral and invasive approaches. Also, ensure that the fluid is released in a regulated manner. A medication for a long amount of time. As a result, a variety of chemical and physical approaches to transdermal patch development are being investigated.
Keywords: Transdermal, permeation pathways, drug delivery, matrix, reservoir