Investigation of the Effect of Methylprednisolone on Neck Pain
Khalil Komlakh
Department of Neurosurgery, School of Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Masoud Hatefi *
School of Medicine, Emam Khomeini Hospital, Ilam University of Medical sciences, Ilam, Iran.
*Author to whom correspondence should be addressed.
Abstract
Background: Chronic Neck pain (NP) is one of the most common problems. Therefore, the present study was conducted with an aim Investigation of the effect of prednisolone on NP.
Methods: In this clinical trial, with 46 patients for the experimental group and 43 patients were analyzed for the control group. The method of selecting individuals in both groups was sequentially, thus all eligible individuals were selected to complete the sample size required. The statistical population of patients with NP was referred to clinics, hospitals and specialist doctors. Data were collected using the VAS pain scale, which was in the range of zero-10, before and after the intervention and analyzed using SPSS16 software.
Result: The results showed that the M (SD) pain score before the intervention in the control group was 7.32±0.47 and in the experimental group was 7.20±0.41(P=0.21, F=6.27). After drug treatment with methylprednisolone in 3 days after M (SD) intervention the pain of patients in the experimental group decreased to 5.50±0.88, in 6 days to 3.60±0.53 and in 9 days to 3.26±0.68(P=0.000).
Conclusions: Due to the positive effect of methylprednisolone on reducing pain in patients with NP, the use of this drug is recommended to reduce pain in these patients.
Keywords: Prednisolone, neck pain, Methylprednisolone