Evaluation of Sinopharm and Sinovac COVID-19 Vaccination Adverse Effects among the Population of Karachi: A Survey Based Study
Ata Ur Rehman *
Department of Pharmacology, Hamdard College of Medicine & Dentistry, Hamdard University, Karachi, Pakistan.
Kiran Khan
Department of Community Medicine, Iqra Medical and Dental College, Karachi, Pakistan.
Jai Dev Maheshwari
Department of Community Medicine, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, Pakistan.
Ghazala Nasim Pasha
Department of Community Health Sciences, United Medical and Dental College, Karachi, Pakistan.
Fatimah Kamran
Baqai Dental College, Baqai University, Karachi, Pakistan.
Nazrah e Zahrah
Baqai Dental College, Baqai University, Karachi, Pakistan.
*Author to whom correspondence should be addressed.
Abstract
Introduction: Vaccines function through a variety of methods to provide disease protection; nevertheless, the process of establishing immunity can create side effects.
Objectives: The purpose of this research was to determine the acute side effects of two COVID–19 immunizations that are commonly used in the Karachi population.
Materials and Methods: Between August and September of 2021, a cross-sectional analytical survey was carried out. The 291 immunization recipients were asked to complete a survey concerning the vaccine's side effects. The Chi-Square test was used to compare the post-vaccination side effects of categorization groups. A p-value of ≤0.05 was statistically significant.
Results: Among post-vaccination side effects, fever was reported by 32.3% of the participants, followed by fatigue, redness at the injection site and gastrointestinal disturbances. The results show association of minor adverse effect with Gender and history of COVID infection.
Conclusion: In conclusion, vaccines are a potent weapon for controlling the COVID-19 pandemic, with high efficacy and low adverse reactions. The most common side effects of the Sinopharm and Sinovac vaccination was found to be fever, and there was a linear association between the presentations of most of the adverse effects and the history of Covid-19 infection.
Keywords: Sinopharm, sinovac, adverse effects, COVID-19, Vaccination