Journal of Pharmaceutical Research International

Background: In-hospital mortality data of patients who have been experiencing ST (stent thrombosis) shows 7.9% statistics for acute stent thrombosis (AST) within 24 hours of PCI, Sub-Acute Stent Thrombosis (SAST) occurs during 30 days of Percutaneous Coronary Intervention (PCI), Late Stent Thrombosis (LST) found 3.8% within the first year after PCI, and Very Late Stent Thrombosis found 3.6% in 1 year after PCI. From our study, we found out the frequency of Acute Stent Thrombosis (AST) in ST-elevation myocardial infarction (STEMI) Patients after Primary Percutaneous Coronary Interventions (PPCI).

Methods: This descriptive-analytic case series was conducted in 06 months data collection time in the NICVD Karachi Pakistan. All the study sample were computed and analyzed by using SPSS (20.0 Version). Mean ± standard deviation was calculated for age, duration of surgery, weight, height, and BMI. Chi-square test by using P ≤ 0.05 as significant on 95% Confidence Interval were used for other variables.

Results: Out of 142 patients of 55.56 years of mean age was evaluated with standard deviation ±12.24 and BMI mean was 27.56±6.28. The mean ± SD duration of surgery was 33.48±9.26.

Conclusion: It is to be concluded that the frequency of AST after primary PCI was found to be significant. Patients presenting with STEMI were at high risk of AST whether they were hemodynamically unstable or they had ACS stenting of multivessel coronary diseases.