Comparison between Opioid Free Anesthesia and Conventional Opioid Based Anesthesia for Patients Undergoing Laproscopic Surgeries under General Anesthesia
Sornam Annamalai
Department of Anesthesiology, Saveetha Medical College and Hospital, Saveetha University, Thandalam, Chennai, Tamil Nadu, India.
Lakshmi Ramakrishnan *
Department of Anesthesiology, Saveetha Medical College and Hospital, Saveetha University, Thandalam, Chennai, Tamil Nadu, India.
Dhivya Ravikumar
Department of Anesthesiology, Saveetha Medical College and Hospital, Saveetha University, Thandalam, Chennai, Tamil Nadu, India.
Karthik Krishna Ramakrishnan
Department of Radiodiagnosis, Saveetha Medical College and Hospital, Saveetha University, Thandalam, Chennai, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
Postoperative pain management plays a vital role in the recovery after surgery. All these days opioids were used to accomplish this, but their use can be associated with adverse effects which can prolong the hospital stay. In the present era of opioid epidemic, it is our responsibility to look for other alternatives, other drugs and modalities which can be safely be given to opioid naive surgical patients. The concept of multi-modal analgesia came as a paradigm shift lately by employing loco regional analgesia as well as drugs acting on different receptors of nociception. One of the pharmaceutical agents is Lignocaine which when given intravenously as continuous infusion produced analgesia in concentrations similar to epidural route. We conducted a study on continuous intra operative infusion of lignocaine in 1mg/kg/hr after a bolus dose. Lignocaine produced better hemodynamic stability, reduced consumption of volatile anaesthetics, less postoperative nausea vomiting, sedation and facilitated early ambulation in patients after laparoscopic surgeries.
Keywords: Opioid-free anesthesia, analgesia, opioid, peri operative period, multi modal analgesia