Synthesis, Characterization and Biological Evaluation N-[5-(1H-indol-3-yl)-1,3,4-thiadiazol-2-yl]methanimine Derivatives
Shruti Hirekurubar
Department of Pharmaceutical Chemistry, Karnataka State Akkamahadevi Women’s University Vijayapur, India.
Sanjeevkumar Giri *
Department of Pharmaceutical Chemistry, Karnataka State Akkamahadevi Women’s University Vijayapur, India.
*Author to whom correspondence should be addressed.
Abstract
A new class of potentially biologically active new 1,3,4-thiadiazol derivatives have been prepared and reported in excellent yields. Its antioxidant properties were examined. It exhibited good activity, which had the highest in vitro anti oxidant properties against DPPH scavenging activity. All these derivatives were characterized by melting point, Fourier-transformation infrared spectroscopy, Nuclear Magnetic Resonan (HNMR and 13C NMR).
Keywords: 1,3,4-thiadiazol, Antioxidant property, FTIR, HNMR and 13C NMR