Study on Effectiveness of Blastocyst Transfer over Cleavage Stage Embryo Transfer in Patients with Failed Conception
Rajvee R. Chokhandre
School of Allied Health Sciences, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India.
Akash More *
Wardha Test tube Baby Centre, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical science, Sawangi (Meghe), Wardha, Maharashtra, India.
Mehul Salve
Department of OBGY, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, Maharashtra, India.
Deepti Shrivastava
Department of OBGY, Director of Wardha Test tube Baby Centre, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, Maharashtra, India.
*Author to whom correspondence should be addressed.
Abstract
Background: IVF has been proved a blessing for many couples. Embryo selection and transfer are key steps in ART. In-vitro fertilization includes embryo transfer either at cleavage stage (day2/ day3) or at blastocyst stage (day5). Implantation rate can be improved by transferring blastocyst stage embryo. Implantation rate may decrease after repeated unsuccessful implantation. This study aims to assess the effectiveness of Blastocyst Transfer in patients with history of failed Cleavage Stage Embryo Transfer.
Methodology: This will be an observational study conducted at Wardha Test Tube Baby Centre, AVBRH. 40 infertile women with history of previous IVF failure will be included in the study. Embryo Transfer will be done at blastocyst stage and βhcg level will be measured on 14th day of embryo transfer.
Expected Results: We expect that blastocyst stage embryo transfer may give more positive result compare cleavage transfer. We predict that transferring embryo at blastocyst stage may increase implantation and pregnancy rate.
Conclusion: Blastocyst stage embryo transfer is effective compared to Cleavage Stage Embryo Transfer.
Keywords: Cleavage stage embryo transfer, blastocyst transfer, in-vitro fertilization, assisted reproduction, b-hcg level, conception