Organophosphorous Compounds in Assessment of Histomorphological Alterations of Natural Tooth
Snega Thamilselvan
Department of Oral & Maxillofacial Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai-77,Tamilnadu. India.
Abirami Arthanari *
Department of Forensic Odontology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai-77,Tamilnadu, India.
R. Abilasha
Department of Oral and Maxillofacial Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, India.
Pratibha Ramani
Department of Oral and Maxillofacial Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, India.
*Author to whom correspondence should be addressed.
Abstract
Background: Pesticide poisoning has indeed been recognized as a significant global health problem, and it is the most common cause of morbidity and mortality.Organophosphorus compounds (OP) are extensively used in agriculture, domestic pest control, and biological agents. Each year, an estimated 25 million farmers in developing countries are poisoned by pesticides, commonly OP, which is known to cause serious health ill effects.
Aim: The aim of this study is to assess the histomorphological alterations in natural tooth due to exposure to different organophosphorous compounds.
Materials and Methods: This research was carried out with organophosphorous compound - ANUFURAN 3G, carbofuran 3% CG purchased from local commercial market. The OP was available as solid crystals which made into a solution by adding 1g of OP compounds to 100ml of distilled water. The natural tooth was immersed in the respective solution for an hour and assessed for morphological &histological alterations through ground sections (200μm).
Results: Visually, there were very mild purplish tint on the cervical and apical 1/3rd of the tooth. Histologically, there were increased enamel lamellae which may have propagated to crack. The dentinal tubules were prominent and the pulpal tissue was completely dissolved.
Conclusion: The OP compounds did not prove to show any morphological or histological alterations to natural tooth.
Keywords: Histomorphological alterations, Natural tooth, Organophosphorus compounds