Diagnosis of Genital Tuberculosis by Cartrdige Based Nucleic Acid Amplification Test in Subfertile Women of Rural Hospital
Asawari Deo *
Department of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College, Sawangi [M], Wardha, India.
Deepti Shrivastava
Department of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College, Sawangi [M], Wardha, India.
Harsha Shekhawat
Department of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College, Sawangi [M], Wardha, India.
Uttara Shelke
Department of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College, Sawangi [M], Wardha, India.
*Author to whom correspondence should be addressed.
Abstract
Tuberculosis has serious extra-pulmonary manifestations that are sometimes difficult to diagnose and thus left untreated. One such manifestation is female - genital tuberculosis (FGTB). Any diagnostic test is not efficient enough to prove the evidence of female genital tuberculosis. High level of clinical examination, detailed history of the patient, systemic examination, a series of tests to document M. tuberculosis as well as imaging techniques for characteristic structural changes are essential for the diagnosis.
There exists lot of diagnostic dilemmas for genital tuberculosis in the available literature.no single test is found confirmatory except for wet culture and histopathological positivity, which may become paucibacillary extrapulmonary sites and time consuming, which creates a need for an investigation which can provide quicker and accurate results. cartridge based nucleic acid amplification test [CBNAAT] being a molecular test may be rapid and promising to diagnose these lesions.
The diagnostic value of CBNAAT in detection of female genital tuberculosis seems to be limited, although it has a high positive predictive value.
Keywords: CBNAAT, genital tuberculosis, FGTB