A Rare Site of Presentation of B Cell Lymphoblastic Lymphoma
Jaistri Jaishankar
Department of General Surgery, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Chengalpattu District, Tamilnadu-603103, India.
K. Senthilkumar
Department of General Surgery, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Chengalpattu District, Tamilnadu-603103, India.
R. Anantharamakrishnan
Department of General Surgery, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Chengalpattu District, Tamilnadu-603103, India.
. Megha
Department of General Surgery, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Chengalpattu District, Tamilnadu-603103, India.
*Author to whom correspondence should be addressed.
Abstract
Lymphoblastic lymphoma is seen accounting to about 2% of all the lymphomas and it is a neoplasm of precursor B cells. Lymphoblastic lymphoma is highly aggressive, but is now frequently curable with recent therapy. Lymphoblastic lymphoma is associated with radiation exposure and also exposure to pesticide. The lymphoblasts infiltrate nodal or extranodal structures and is commonly associated with large mediastinal masses with a high chances for spreading to bone marrow and the central nervous system. The prognosis in all age groups has drastically improved with the use of intensive ALL-type chemotherapy regimes, with a disease-free survival of 73-90% in children and 45-72% in adults.
Keywords: B. cell, lymph nodes, bone