Anti Inflammatory Activity of Herbal Formulation Prepared Using Mint and Green Tea
R. Pon Preeja
Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
Lakshminarayanan Arivarasu *
Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
Rajesh Kumar
Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai-77, Tamil Nadu, India.
Lakshmi Thangavelu
Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai-77, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
Aim: The aim of my study is to evaluate the anti-inflammatory activity of herbal formulation prepared using mint and green tea.
Introduction: Green tea is a ‘non-fermented’ tea, and contains more catechins than black tea or oolong tea. Green tea and epigallocatechin 3-gallate, suppress the gene and/or protein expression of inflammatory cytokines and inflammation-related enzymes.Mint have a potent anti-inflammatory activity in the croton oil-induced mouse ear edema model.
Materials and Method: Preparation of herbal formulation:
To 100 ml of distilled water,1 g of tea leaves and 1 g of powdered mint is added .This mixture was heated for about 15-20 minutes and then filtered using filter paper.The mixture was again heated and concentrated from 70 ml to 20 ml.
Result: At 20 μl there is 59 percent of inhibition,at 50 μl there is 90 %of inhibition ,whereas in the standard there is only 40%of inhibition .Thus as the concentration increases the anti-inflammatory activity of the extract increases.
Conclusion: From this study we can conclude that green tea and mint have a great anti-inflammatory property.Anti-inhibitory zone ranging from 90 and is indicating that it is higher than the standard diclofenac sodium which has only 40% of inhibition.
Keywords: Green tea, mint, anti-inflammatory, epigallocatechin