Anti-inflammatory Activity of Selenium Nanoparticles Synthesised Using Pterocarpus santalinus
A. Shivapriya Raje Bhonsle
Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
Lakshminarayanan Arivarasu *
Department of Pharmacology, Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamilnadu, India.
S. Rajeshkumar
Department of Pharmacology, Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamilnadu, India.
Lakshmi Thangavelu
Department of Pharmacology, Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamilnadu, India.
*Author to whom correspondence should be addressed.
Abstract
Introduction: Inflammation is a biochemical response of the immune system that can be caused by a wide range of factors, including bacteria, infected cells and toxic substances.Pterocarpus Santalinus L. f. (Fabaceae) is most commonly referred to as red sandalwood in English, but it also has several common names in many languages , The aim of the study was to evaluate the anti inflammatory activity of Pterocarpus Santalinus.
Materials and Methods: The plant extract was prepared and then the selenium nanoparticles were further synthesized. This has been regularly found in UV-vis spectrophotometers. This assay has the potential to calculate extracts by adding hydrogen to DPPH radicals. Pterocarpus Santalinus at different concentrations measured by the inhibition of albumin denaturation assay. In recent times, attention has continued to be paid to natural products and drugs as anti-inflammatory, based on reactions with free radicals and other reactive species. Further, increase in the concentration in turn increases the percentage of inhibition.
Results: In the present study, it was found that the biosynthesized selenium nanoparticles had potent anti-inflammatory activity.
Keywords: Pterocarpus santalinus, anti-inflammatory activity, UV-vis spectroscopy, selenium nanoparticles, nanotechnology