Review on Chitosan Intake and Enhancement in Fecal Excretion of Endocrine Disruptors
Bhuvaneswari Ponnusamy
Department of Biochemistry, Saveetha Institute of Medical and Technical Sciences, Saveetha Dental College and Hospitals, Saveetha University, Chennai-600 077, India.
U. Vidhya Rekha
Department of Public Health Dentistry, Sree Balaji Dental College and Hospital, Chennai-600 100, India.
Ponnulakshmi Rajagopal
Department of Central Research Laboratory, Meenakshi Ammal Dental College and Hospitals, Meenakhsi Academy of Higher Education and Research (MAHER), Chennai-600 095, India.
Durairaj Sekar
Cellular and Molecular Research Centre, Saveetha Dental College & Hospitals, Saveetha Institute of Medical & Technical Sciences, Saveetha University, Chennai - 600 077, India.
Selvaraj Jayaraman *
Department of Biochemistry, Saveetha Institute of Medical and Technical Sciences, Saveetha Dental College and Hospitals, Saveetha University, Chennai-600 077, India.
*Author to whom correspondence should be addressed.
Abstract
Chitin is most abundantly found non-digestible carbohydrate similar to cellulose. It has gained a lot of interest in last few years due to its wide range of applications. They are used as an alternative, dietary supplement. Chitin on deacetylation forms chitosan, an active component of chitin. The degree of deacetylation and molecular weight are the factors that elucidate varying degree of biological property of chitosan. The ability of chitosan in fat and lipid excretion has obtained keen eye among various researchers. This property of chitosan is made use in enhancing the elimination of various harmful environmental lipophilic xenobiotics. Endocrine disruptors are a group of environmental pollutants causing various hazardous effects in living system. They are highly lipophilic, persistent and can accumulate in various tissues. Thus correlating the ability of chitosan to increase excretion of fats and lipophilic xenobiotics showed a promising positive outcome.
Keywords: Endocrine disruptors, chitosan, dietary fiber, biomedical applications, endocrine disruptor’s excretion