Journal of Pharmaceutical Research International

Introduction: Arterial vascular occlusion can be caused by an embolus or acute thrombosis. Acute arterial occlusion can be induced by iatrogenic damage, such as that produced by the insertion of invasive catheters used for arteriography. It can occur as a result of PTA or stent implantation, the use of an intraaortic balloon pump, or IV drug addiction. Other causes include fractures, crush injuries, and penetrating wounds that change the intima of the artery. Reliable identification of an arterial blockage as embolic or thrombotic in origin is necessary to begin appropriate therapy.

Clinical Findings: On examination vitals was heart rate is 80 beats/min respiration 22beats/min blood pressures 120/80 mmHg temperature 97^oF the chest was clear, patient is oriented on local examination gangrene over left lower limb, RTPCR test was done and patient was put in isolation ward and on day 3 the RTPCR report is negative.

Diagnostic Evaluation: Coagulation profile APTT-31.5, PT-16.5, INR-1.28, UREA-16, SODIUM-128, POTASSIUM-4.3, RTPCR-NEGATIVE, HBSAG-NON-REACTIVE, HCV-NONREACTIVE.

Therapeutic Intervention:  The patient was taken to the catheterization lab and local anesthesia is given and balloonplasty was done using ARMADA 4MM X 120cm with that Inj. Urokinase 1.5 Lac IU is given stat by infusion the

Conclusion: My patient aged 24 years male was admitted to Cardiac unit in AVBRH hospital Sawangi (M) Wardha on date 25/03/2021 for visit in hospital OPD with complaints of leg pain with redness and swelling over the leg.