Antibacterial and Antioxidant Activity of Garcinia mangostana Mediated Selenium Induced Nanoparticles: An In vitro Study
J. Georgia Benitha *
Department of Oral and Maxillofacial Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamilnadu, India.
Pratibha Ramani
Department of Oral and Maxillofacial Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamilnadu, India.
S. Rajeshkumar
Department of Oral and Maxillofacial Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamilnadu, India.
S. Gheena
Department of Oral and Maxillofacial Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamilnadu, India.
R. Abhilasha
Department of Oral and Maxillofacial Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamilnadu, India.
K. Reshma
Department of Oral and Maxillofacial Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamilnadu, India.
*Author to whom correspondence should be addressed.
Abstract
Introduction: The biosynthesis of selenium nanoparticles (SeNPs) has gained interest due to their unique chemical and biological properties, which are critical for their possible applications in a variety of fields. Garcinia mangostana (mangosteen) is a tropical fruit known for its edible pulp. The edible pulp accounts for just 30% of the total fruit weight, while the pericarp and seed are discarded. In response to rising public demand for naturally safe foods and items, we conducted a study to determine the antioxidant ability and antibacterial activity of mangosteen pericarp induced with selenium nano particles.
Methods: The antioxidant capacities of selenium nano particles induced mangosteen’s pericarp were determined using 2,2- diphenyl-1-picrylhydrazyl (DPPH) assay, whereas agar well – diffusion technique was used to assess the antibacterial activity on chosen oral pathogens such as Streptococcus mutans, Staphylococcus aureus, Enterococcus faecalis.
Results: In this study, the G. mangostana mediated selenium nanoparticles were synthesized using a green synthesis method. The maximum absorbance of the synthesized selenium nanoparticles was measured using a double beam UV visible spectrophotometer, resulting in a maximum absorbance of 325 nm. The Garcinia mangostana pericarp extract mediated selenium nanoparticles shows potent antimicrobial and antioxidant activity.
Conclusion: The outcomes of our study could facilitate future application of mangosteen waste as a bio preservative in the food industry.
Keywords: Selenium nanoparticles, Garcinia mangostana extract, pericarp, antioxidant, antimicrobial