Neutrophil-lymphocyte Ratio as a Bio- Inflammatory Prognostic Marker of Fetomaternal Outcomes of Preeclampsia: A Narrative Review
Neema Acharya
Department of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College (DMIMSU), Sawangi, Wardha 442001, Maharashtra, India.
Shazia Mohammad *
Department of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College (DMIMSU), Sawangi, Wardha 442001, Maharashtra, India.
Shirin Mohammad
Medical Practitioner, Self-Employed, Maharashtra, India.
Sourya Acharya
Department of Medicine, Jawaharlal Nehru Medical College (DMIMSU), Sawangi, Wardha 442001, Maharashtra, India.
Samarth Shukla
Department of Pathology, Jawaharlal Nehru Medical College (DMIMSU), Sawangi, Wardha 442001, Maharashtra, India.
*Author to whom correspondence should be addressed.
Abstract
Background: Preeclampsia & its related problems have potential contribution to maternal mortality & morbidity. Early diagnosis & appropriate management of preeclampsia can prevent antenatal, intranatal & postnatal complications associated with preeclampsia. The neutrophil to lymphocyte ratio (NLR) which is derived from a complete blood count & dedifferentiation, is a straightforward inflammatory index (1). Pre-existing studies have shown that NLR is indicator of Preeclampsia.
Objective of this Narrative Review: In this we summarized the evidence regarding the clinical utility of NLR in preeclampsia & its related complications.
Methods: A comprehensive systematic search from PubMed, Embase, Cochrane Library, VIP database for relevant literature. Sensitivity, specificity & other measures of accuracy of NLR for the diagnosis of PE were pooled.
Keywords: NLR, preeclampsia, fetomaternal outcomes, biomarker