Association of Total Ischemic Times and In-Hospital Outcomes of Acute STEMI Patients who Underwent Primary Angioplasty at a Tertiary Cardiac Care Facility
Arshad Ali Shah
Dow University of Health Sciences Karachi, Pakistan.
Syed Dilbahar Ali Shah
Dow University of Health Sciences Karachi, Pakistan.
Muhammad Sami Khan
Sindh Institute of Urology and Transplantation Karachi, Pakistan.
Faisal Ahmed
Dow University of Health Sciences Karachi, Pakistan.
Iftikhar Ahmed
National Institute of Cardiovascular Diseases Karachi, Pakistan.
Fawad Farooq
National Institute of Cardiovascular Diseases Karachi, Pakistan.
Dileep Kumar *
National Institute of Cardiovascular Diseases Karachi, Pakistan.
*Author to whom correspondence should be addressed.
Abstract
Aims: To determine the association between total ischemic time and in-hospital outcome of acute ST elevation myocardial infarction (STEMI) patients who underwent primary angioplasty.
Study Design: Prospective observational study.
Place & Duration of Study: Department of Cardiology, Dow university of health sciences Karachi between October 2017 till March 2021.
Methodology: Data for total ischemic time analysis were collected from 366 STEMI patients who consecutively underwent primary angioplasty. Total ischemic time was measured from the onset of chest pain to o the first balloon inflation during primary angioplasty and in hospital outcome was measured.
Results: Total ischemic times were available in 366 STEMI patients which was ≥ 30 minutes and < 24 hours: ≤ 2 hours in 15.5%, >2-3 hours in 11.4%, >3-5 hours in 25.4%, and >5 hours in 47.5% of STEMI patients. In addition, STEMI patients with total ischemic times <5 hours demonstrated complete ST-segment resolution and reduced death rate than those with total ischemic times >5 hours.
Conclusion: This study showed that shorter ischemic times are significantly related to improved myocardial reperfusion and decreased mortality.
Keywords: ST-segment elevation myocardial infarction, total Ischemic time, primary angioplasty, outcomes