Bullous Disease of Diabetes (Bullosis Diabeticorum)
Mohammed Salah Hussein
Department of Gastroenterology and Endoscopy, Dr. Samir Abbas Hospital, Jeddah, Saudi Arabia and Department of Internal Medicine, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Shatha Saeed Mohammed Alqahtani
Huraymala General Hospital, Saudi Arabia.
Amani Hussain Almutawa
Huraymala General Hospital, Saudi Arabia.
Batool Mesfer Alqahtany
Huraymala General Hospital, Saudi Arabia.
M. Albulushi Amer Ismail
Huraymala General Hospital, Saudi Arabia.
Ayat Hussain Almutawa
King Faisal University, Saudi Arabia.
Alaa Saleh Alharbi
Rumah General Hospital, Saudi Arabia.
Elaf Saad Almutairi
Huraymala General Hospital, Saudi Arabia.
Maab Jassim Alhashim
Imam Abdulrahman Bin Faisal University, Saudi Arabia.
Sarah Naif Aldawish
Alshifa Primary Health Care, Saudi Arabia.
Hassan Ali A. Almohaishi
Taibah University, Saudi Arabia.
Hamed Hamad B. Alharbi
King Fahad Specialist Hospital, Buraydah, Saudi Arabia.
Mohammed Nabil A. Almuhanna
King Saud Bin Abdulaziz University for Health Science, Saudi Arabia.
Dhiyaa Jaber Alfaraj
Imam Abdulrahman Bin Faisal University, Saudi Arabia.
Abdulrahman Saud Saeed Alsharari
King Faisal Hospital Qurayat, Saudi Arabia.
*Author to whom correspondence should be addressed.
Abstract
Acanthosis nigricans, acrochordrons, diabetic dermatopathy, necrobiosis lipoidica, and bullous diabeticorum are some of the cutaneous symptoms of diabetes. Bullous illness (bullosis diabeticorum) is a blistering, non-inflammatory condition of the acral skin. Diabetes bullous illness is more common in people who have had diabetes for a long time or who have many comorbidities. Although the actual cause is uncertain, it is likely to be multifactorial. Neuropathy, nephropathy, vasculopathy, and UV (ultraviolet) light are all suggested to have a role. BD is most likely caused by the various problems that come with poorly managed diabetes. The exact number of people who have BD is unknown. The majority of case studies in the literature were based on a small number of cases. Bullous diabeticorum is a restrictive diagnosis, which necessitates a histological study that includes direct immunofluorescence to rule out other vesicobullous illnesses. In terms of BD management, no strong consensus has formed. The blisters have historically been thought to be self-limiting, with bullae resolving in 2 to 6 weeks if left untreated. In some cases antibiotic may be used. In this article we’ll be looking at Bullosis Diabeticorum. Its etiology, epidemiology, diagnosis, and treatment.
Keywords: Bullous disease, diabetes, diabetic dermatopathy