An Extensive Review on Chitosan as Versatile Material for Pharmaceutical and Biomedical Application
Shivangi Abrol
University Institute of Pharma Sciences (UIPS), Chandigarh University, Ludhiana Mohali Highway, Punjab, India.
Hitesh Kumar Dewangan *
University Institute of Pharma Sciences (UIPS), Chandigarh University, Ludhiana Mohali Highway, Punjab, India.
*Author to whom correspondence should be addressed.
Abstract
Chitosan is a polysaccharide and is derived from chitin. Chitosan every now and then referred to as a soluble chitin. chitosan is strongly basic polysaccharide. chitosan shows physiochemical and biological properties. This review presents the common source for chitosan manufacturing that is crabs and shrimp. According to researchers it is just a fat inhibitor. some of the application of chitosan in pharmaceutics/drug delivery and in biomedical field are also highlighted. Chitosan act as a diluent, as mucoadhesive excipient, as permeation enhancer, in vaccines delivery, as parenteral delivery, chitosan as food additive, cosmetics industry. chitosan also has a number of medicinal benefits. Chitosan is employed in a variety of applications because it is soluble in acidic aqueous conditions (food, cosmetics, biomedical and pharmaceutical applications). We give a quick overview of the chemical modifications of chitosan, a field in which a number of syntheses have been proposed but not yet realised on a large scale. This review focuses on current articles on these materials' high-value-added applications in medicine and cosmetics.
Keywords: Chitosan, structure, application, biomaterials