COVID- 19 Infections with and without Co-morbidities and Clinical Outcome
Beenish Ghafar
Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Urooj Bhatti *
Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Shehmeen Khan
Bilawal Medical College, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Afsheen Abro
Bilawal Medical College, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Rubina Ahmedani
Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Quratulain Memon
Department of Surgical Ward, Jinnah Postgraduate Medical Center, Karachi, Pakistan.
*Author to whom correspondence should be addressed.
Abstract
Aim: To evaluate the clinical outcomes and severity of disease in COVID-19 patients presenting with and without comorbidities.
Study Design: Cross-sectional study.
Place and Duration: ICUs, wards of Jinnah Postgraduate Medical Center Karachi from March, to June 2021.
Methodology: The enrolled patients diagnosed with COVID-19 ie according to the provisional directions given by WHO, were assessed for clinical outcomes. Comorbidities were determined based on patients self-report on admission.
Results: Total 200 COVID patients were enrolled in the study, out of them 179 were with comorbidities like type 2 Diabetes mellitus, hypertension, cardiac disorders and asthma, while 21 COVID patients were with no co morbidity. In present study (n=200), 55.5% were belonging to the age group more than fifty five years old, there were 50.5% males and 29.5% patients came in the month of June 2021. There were 84% hypertensive, 54% were diabetic, 10% were Ischemic Heart Disease and 5% were Asthmatic patients. Clinical outcomes, i.e., pneumothorax, pulmonary embolism, Myocardial Infarction, septic shock, heart failure, Disseminated Intravascular Coagulation was compared regarding associated co-morbidities at the time of admission, p-value was <0.01 and x2=20.15 .
Conclusion: COVID patients with comorbidities are more at risk of developing worst clinical outcomes.
Keywords: COVID 19, co-morbidities, clinical outcomes