Combined Effect of Walking and Vitamin D Intake on Patients with Heart Failure

Muhammad Usama Javed

Allied Hospital, Faisalabad Medical University, Faisalabad, Pakistan.

Tanzeel ur Rehman Mustafa

Allied Hospital, Faisalabad Medical University, Faisalabad, Pakistan.

Sharoz Mukhtar Shah

Allied Hospital, Faisalabad Medical University, Faisalabad, Pakistan.

Iza Babar

DHQ Hospital, Toba Tek Singh, Pakistan.

Fatima Maham Iqtidar

Allied Hospital, Faisalabad Medical University, Faisalabad, Pakistan.

Muhammad Arslan Babar *

Allied Hospital, Faisalabad Medical University, Faisalabad, Pakistan.

*Author to whom correspondence should be addressed.


Abstract

Objective: Patients with heart failure may benefit from vitamin D treatment, according to new research (Congestive Heart Failure).

Methods: In our current nonrandomized clinical research, 43 individuals with dilated cardiomyopathy who did not exhibit substantial gains in physical functioning with optimum heart failure therapy were included. Twelve weeks of weekly vitamin D supplements (200,000 IU) were added to the heart failure therapy to help improve the patient's condition. On the other hand, researchers looked at how it affected the 6-minute walk distance and pro-BNP levels. To analyses the data, we utilized SPSS version 19. Accordingly, we utilized random samples t-tests to assess the substantial role of vitamin D supplementation on pre-intervention vitamin D level, 6-minute walk distance, and pro-BNP level, respectively. Significance was defined as an alpha value less than 0.01.

Results: Individuals in NYHA class II (66%) were the majority, while those in NYHA classes I, III and IV were represented by 18%, 8% and 5%, accordingly. Following 14 weeks of vitamin D treatment, the group's mean vitamin D level was increased from 17.596.57ng/ml at baseline to 32.974.65ng/ml (p0.0006). Pre-intervention mean distance travelled was 806382ft, however after the intervention it rose to 945392ft (p-value 0.07). While before the intervention, the mean per-BNP level of research participant was 1025-636, and after intervention, it had enhanced to 160-80--a statistically significant improvement (p=0.005).

Conclusion: According to a decline in blood pro-BNP characterized by an increase in six-minute walk distance, vitamin D administration decreases the intensity of heart failure.

Keywords: Vitamin D, congestive heart failure, older adults


How to Cite

Usama Javed, M., Mustafa, T. ur R., Shah, S. M., Babar, I., Iqtidar, F. M. and Arslan Babar, M. (2021) “Combined Effect of Walking and Vitamin D Intake on Patients with Heart Failure”, Journal of Pharmaceutical Research International, 33(50B), pp. 55–59. doi: 10.9734/jpri/2021/v33i50B33427.