Utility of Microvessel Density (MVD) by CD34 in Different Histological Grades of Oral Squamous Cell Carcinoma
Ayushi Singh *
Department of Pathology, Jawaharlal Nehru Medical College, Sawangi, India.
Miheer Jagtap
Department of Pathology, Jawaharlal Nehru Medical College, Sawangi, India.
Samarth Shukla
Department of Pathology, Jawaharlal Nehru Medical College, Sawangi, India.
Sunita Vagha
Department of Pathology, Jawaharlal Nehru Medical College, Sawangi, India.
*Author to whom correspondence should be addressed.
Abstract
Oral squamous cell carcinoma is one of the leading causes of cancer related death and is preventable. Different grade at which a carcinoma presents determines the treatment modality and prognosis of the disease. Microvessel density measures formation of new vessels around tumor mass and is very important criteria for tumor metastasis and disease spread. Immunohistochemistry provide very definitive measures to determine the micro vessel density. Our study showed a positive correlation between Microvessel density and tumor size and dysplasia.
Keywords: Oral squamous cell carcinoma, CD 34, microvessel density