Review on Drug Utilization Assessment of Cephalosporin
Awais Ahmed Juno
Department of Pharmacy Practice, Faculty of Pharmacy, Ziauddin University, Karachi, Pakistan.
Mirza Tasawer Baig
*
Department of Pharmacy Practice, Faculty of Pharmacy, Ziauddin University, Karachi, Pakistan.
Aisha Jabeen
Department of Pharmacology, Faculty of Pharmacy, Ziauddin University, Karachi, Pakistan.
Shahzada Azam Khan
Memon Medical Institute Hospital, Karachi, Pakistan.
Saleem Ahmed khoso
National Institute of Child Health, Karachi, Pakistan.
Sultan Othman Alolayan
Clinical and Hospital Pharmacy Department, College of Pharmacy, Taibah University, Al-Madinah Al-Munawarah, Saudi Arabia.
*Author to whom correspondence should be addressed.
Abstract
Pediatric is the field of medicine that is concerned with the health of infants, children and adolescents. Globally, many infectious diseases have been controlled in the 20th century by improving People’s standard of living through public health campaigns and the use of various antimicrobial agents. Evidence suggests that the manner in which Primary Healthcare centers prescribe drugs has contributed to the high rise in Anti-Microbial Resistance (AMR). The extent of the resistance is determined by the site of antibiotic application and in this study oral usage of antibiotics was found to be the highest contributor to Anti-Microbial Resistance. A systematic review of the published literature on the conduct and reporting of meta-analyses in observational studies was done using databases searched included MEDLINE, Educational Resources Information Center, PsycLIT (http://www.wesleyan.edu/libr), Google Scholar, EMBASE, International Pharmaceutical Abstracts and the Current Index to Statistics. It was concluded that most of the articles reported that cephalosporin were widely used antibiotics and therefore its use must be rational; to avoid its abuse which may result to high level of resistance.
Keywords: Pediatric, antimicrobial resistance, meta-analyses, medicine