Modern Solutions in the Treatment of HIV: From Antiretroviral Drug Therapy to Human Genome Editing
Milana Ruslanovna Sebaeva
Chechen State University, Grozny, Chechen Republic, Russia.
Iman Vladimirovna Gelogaeva
Chechen State University, Grozny, Chechen Republic, Russia.
Naida Ramizovna Suleymanova
Dagestan State Medical University, Makhachkala, Dagestan Republic, Russia.
Kamila Umarovna Balaeva
North Ossetian State Medical Academy, Vladikavkaz, Republic of North Ossetia, Russia.
Aishat Arslanovna Dauletova
North Ossetian State Medical Academy, Vladikavkaz, Republic of North Ossetia, Russia.
Zuhra Magomedovna Zakoroeva
North Ossetian State Medical Academy, Vladikavkaz, Republic of North Ossetia, Russia.
Saida Hanbertovna Kasheshova
North Ossetian State Medical Academy, Vladikavkaz, Republic of North Ossetia, Russia.
Takis Albertovich Kozmov *
Rostov State Medical University, Rostov-on-Don, Russia.
Madina Muslimovna Minatulaeva
North Ossetian State Medical Academy, Vladikavkaz, Republic of North Ossetia, Russia.
Alina Yuryevna Maslova
Socmedica, Skolkovo, Russia.
*Author to whom correspondence should be addressed.
Abstract
The human immunodeficiency virus (HIV) belongs to a group of anthroponotic viral diseases that cause HIV infection in the human body, apotheosely transforming into acquired immunodeficiency syndrome (AIDS). HIV infection, in people without adequate treatment, can lead to serious damage to the immune system (hereinafter referred to as IS), which leads to a sharp decrease in resistance to conditionally pathogenic microbes, as well as to the prevalence of oncological pathologies that may lead to death. Due to its simplicity, convenience, efficiency and cost-effectiveness, CRISPR/Cas has found application in a short period of time in a wide variety of fields of fundamental and applied medicine and biotechnology.
Keywords: HIV, antiretroviral therapy, genetic engineering, genome editing