A Review on the Reported Antibacterial Activity of 1,3,5-Triazine
Mrinmoy Basak
Faculty of Pharmaceutical Science, Assam Down Town University, Guwahati-26, Assam, India.
Biplab Kumar Dey
Faculty of Pharmaceutical Science, Assam Down Town University, Guwahati-26, Assam, India.
Sajidul Hoque Ansari
NEF College of Pharmacy, India.
Moksood Ahmed Laskar
Faculty of Pharmaceutical Science, Assam Down Town University, Guwahati-26, Assam, India.
Priyanka Goswami
Faculty of Pharmaceutical Science, Assam Down Town University, Guwahati-26, Assam, India.
Rosamund Jyrwa
Faculty of Pharmaceutical Science, Assam Down Town University, Guwahati-26, Assam, India.
Pal Gogoi
Faculty of Pharmaceutical Science, Assam Down Town University, Guwahati-26, Assam, India.
Md. Rejwan Ahmed Choudhury *
Faculty of Pharmaceutical Science, Assam Down Town University, Guwahati-26, Assam, India.
*Author to whom correspondence should be addressed.
Abstract
Antibiotics are the class of drugs used for bacterial, viral & fungal infection. Antibiotic resistance is the ability of microorganism to withstand themselves against the effects of a drug. Every year antibiotic resistance causes more than 38000 deaths in Thailand, 23000 deaths in USA. In South Asia one new born child dies every 5 minutes from blood stream infection because antibiotics given are ineffective due to bacterial resistance. Now antibiotic resistance is a threat to global health. In this paper, triazene derivatives are kept in concern. Triazines are six-membered, nitrogen-containing heterocyclic scaffold with a wide range of pharmaceutical properties such as antibacterial, antifungal, anticancer, antioxidants, antitubercular, antimalarial and anti-inflammatory. Due to lack of new antibiotics as well older antibiotic are rapidly proving ineffective, derivatives of triazine would be of great significance in future prospective.
Keywords: Triazine, antibacterial, antifungal