Determining the Glycemic Index of Nutritional Product for Diabetes Mellitus- Np through Measuring Glycemic Responses to Reference Food (Glucose) and Test Food (Nutritional product -Np)
Nguyen Thi Diep Anh *
National Institute of Nutrition, Hanoi, Vietnam.
Nguyen Trong Hung
National Institute of Nutrition, Hanoi, Vietnam.
Tran Thi Tra Phuong
Nutrition and Sports, Exercise Medicine Centers System – Nutrihome, Vietnam.
Le Thi Hang
National Institute of Nutrition, Hanoi, Vietnam.
Dinh Tran Ngoc Huy
Banking University HCMC, Ho Chi Minh City Vietnam - International University of Japan, Japan.
Vu Thi Thu Hien
National Institute of Nutrition, Hanoi, Vietnam.
Bui Thi Thuy
National Institute of Nutrition, Hanoi, Vietnam.
Ngo Thi Thu Huyen
National Institute of Nutrition, Hanoi, Vietnam.
Le Thi Tuyet Nhung
Andrologyand Fertility Hospital of Hanoi, Vietnam.
Nguyen Thi Luong Hanh
National Institute of Nutrition, Hanoi, Vietnam.
Tu Thi Mai
National Institute of Nutrition, Hanoi, Vietnam.
Truong Tuyet Mai
National Institute of Nutrition, Hanoi, Vietnam.
Nguyen Hong Truong
National Institute of Nutrition, Hanoi, Vietnam.
Le Danh Tuyen
National Institute of Nutrition, Hanoi, Vietnam.
*Author to whom correspondence should be addressed.
Abstract
The objective was to determine the glycemic index (GI) of Nutritional product for Diabetes Mellitus through measuring glycemic responses to reference food (Glucose) and test among nutritional product 13 participants. The study was a self-controlled clinical trial with 13 qualified participants (8 men and 5 women). They were required to go through the study protocol with reference food and test food. For each individual, seven blood samples were taken in the fasting state and at 15, 30, 45, 60, 90 and 120 minutes after ingestion. Our results show that at all measurement points, the blood glucose levels after consumption of test food were lower than after consumption of reference food. The incremental area under the curve (iAUC) and a GI value of Nutritional product (NP) were calculated for each meal. Mean ± SD of GI value was calculated for test food for the combined group of subjects. Mean iAUC and GI value of Nutritional product were 62,1 ± 12,5 mmol·min/L and 44,9 ± 7,2, significantly lower to those of reference food, which were 132,6 ± 14,8 mmol·min/L and 100, respectively. Finding from the study demonstrated that Nutritional product (GI = 44,9) would be classified as a low – GI food.
Keywords: Clinical trial, glycemic index, nutritional product, national institute of nutrition