Prospective Evaluation of Vitamin D Supplementation on Peripheral Neuropathy in Type 2 Diabetes Mellitus -A Review
Faisal Suliman Algaows *
King Abdulaziz Medical City, National Guard , Iskan PHC, Saudi Arabia.
Fatema Abdullah Althkerallah
King Faisal University, Saudi Arabia.
Norah Abdulmohsen Alsuwailem
Imam Abdulrahman Bin Faisal University, Saudi Arabia
Amnah Abdulnasser Mawlan Ahmed
Durrah Madina PHC, Saudi Arabia.
Razan Fahad Alwagdani
Taif University, Saudi Arabia.
Sarh Abdulhameed Alomran
Arabian Gulf University, Bahrain.
Bayan khalid Y. Alwasifir
Jordan University of Science and Technology, Jordan.
Ohoud Muqbil Almutairi
King Abdulaziz University, Saudi Arabia.
Hawra Abdulmohsen Alfrdan
Imam Abdulrohman Bin Fisal University, Saudi Arabia.
Ziad Saloum Aldebas
Bader 2 PHCC (MOH), Saudi Arabia.
Khuolod Saeed Alqahtani
King Faisal University, Saudi Arabia.
Alaa Abdulrahman Alfayez
King Faisal University, Saudi Arabia.
A. Alfadhli, Rahaf Fahad
Imam Mohammad Ibn Saud Islamic University, Saudi Arabia.
*Author to whom correspondence should be addressed.
Abstract
Diabetic neuropathy is a long-term consequence of diabetes that can cause significant morbidity and a decline in quality of life in many individuals. Low vitamin D levels, in addition to causing rickets in infants and chondrosteoma in adults, may have a role in the development of DM and its underlying disorders, according to a growing body of evidence. Vitamin D deficiency has been linked to type 1 or type 2 diabetes, as well as the microvascular and macrovascular problems that come with it. Vitamin D insufficiency has been linked to diabetic peripheral neuropathy (DPN) as an independent risk factor. Vitamin D, both topical and oral, has been shown to considerably improve DPN symptoms and pain.
Keywords: Type 2 diabetes mellitus, neuropathy, vitamin D supplementation