Design Space by Design of Experiments
Sushant Dangat
School of Pharmacy, Dr. Vishwanath Karad MIT World Peace University, Paud Road, Kothrud, Pune 411038, India.
Deep Patel
School of Pharmacy, Dr. Vishwanath Karad MIT World Peace University, Paud Road, Kothrud, Pune 411038, India.
Ashwin Kuchekar *
School of Pharmacy, Dr. Vishwanath Karad MIT World Peace University, Paud Road, Kothrud, Pune 411038, India.
*Author to whom correspondence should be addressed.
Abstract
The quality of methods and products are usually influenced by several input factors. Research has recently focused on understanding the effects of multidimensional and interconnected input factors on the results of pharmaceutical products and analytical methods using Design of Experiment (DoE). Furthermore, it examines how DOE may be implemented, both for students and teachers, as well as highlighting historical perspectives on DOE. A good experimental design can help you make the most use of the available resources and make the analysis of the results easier. Collaborations between researchers and practitioners that are pushing the boundaries of experimental design are examined. It provides an overview of the principles and applications of the most common screening and response surface design, as well as creating mixtures designs.
Keywords: Design of experiments, design space, screening designs, factorial designs, response surface plots