The Effect of Honey Saffron Syrup on Labor Progression in Nulliparous Women

Main Article Content

Sheno Ghaderi
Farzaneh Zaheri
Bijan Nouri
Roonak Shahoei

Abstract

Background: Labor duration is one of the factors affecting the pregnancy outcome. Objective of the present study is to determine the effect of honey saffron syrup on the labor progression in nulliparous women.

Methods: The nulliparous women with inclusion criteria were randomly divided into three equal groups. For first group, the saffron syrup prepared with honey and for second group, saffron syrup prepared with sugar and in the control group the placebo were orally administered every two hours. Collected data were analyzed using Fisher’s test, ANOVA with Fisher’s post hos test and Repeated measure statistical method with p <0.05 as significant.

Results: The mean of labor duration in the two intervention groups was significantly shorter than the control group (p=0.000). The duration of the first stage of labor in the honey saffron syrup group was significantly shorter than the sugar saffron syrup group (p=0.016).

Conclusion: Administration of saffron syrup with honey shortened the time of first, second and third stage of labor.

Keywords:
Saffron, honey, labor, term pregnancy, nulliparous

Article Details

How to Cite
Ghaderi, S., Zaheri, F., Nouri, B., & Shahoei, R. (2019). The Effect of Honey Saffron Syrup on Labor Progression in Nulliparous Women. Journal of Pharmaceutical Research International, 28(4), 1-8. https://doi.org/10.9734/jpri/2019/v28i430208
Section
Original Research Article

References

Golmakani N, Pourshirazi M, Ebrahimzadeh Zagami S, Esmaeili H, Tara F. The relationship between Cormic Index and labor progress. The Iranian Journal of Obstetrics, Gynecology and Infertility. 2015;18(175):7-15. [In persian].

Salari P, Alavian F, Habibi Rad A, Tara F. The relationship between stress, anxiety and pain with salivary cortisol levels in first stage of labor in primiparous women. The Iranian Journal of Obstetrics, Gynecology and Infertility. 2013;16(55):14-21. [In persian].

Marshall JE, Raynor MD. Myles' Textbook for Midwives E-Book: Elsevier Health Sciences; 2014.

Cunningham F, Leveno K, Bloom S, Spong CY, Dashe J. Williams obstetrics,25e: Mcgraw-hill; 2018.

Alijahan R, Kordi M. Risk factors of dystocia in nulliparous women. Iranian Journal of Medical Sciences. 2014;39(3):254-60. [In persian].

Khalily M, Rezaei MSD. Monitoring the progress of labor in primiparous women using Partograph. JCRPS. 2012;1(3):38-43. [In Persian].

Haseli A, Akbari M, Neisani Samani L, Haghani H, Jahdi F. The effect of abdominal massage along with breathing techniques during labor on duration of uterine contractions in primiparous women. The Iranian Journal of Obstetrics, Gynecology and Infertility. 2017;20(3):1-8. [In Persian].

Al-Qudsi F, Ayedh A. Effect of saffron on mouse embryo development. J Am Sci. 2012;8:1554-68. [In persian].

Mousavi SZ, Bathaie SZ. Historical uses of saffron: Identifying potential new avenues for modern research. Avicenna Journal of Phytomedicine. 2011;1(2):57-66. [In persian].

Kianbakht S. A systematic review on pharmacology of saffron and its active constituents. Journal of Medicinal Plants. 2008;4(28):1-27. [In Persian].

Sadi R, Mohammad-Alizadeh-Charandabi S, Mirghafourvand M, Javadzadeh Y, Ahmadi-Bonabi A. Effect of saffron (Fan Hong Hua) on the readiness of the uterine cervix In term pregnancy: A placebo-controlled randomized trial. Iranian Red Crescent Medical Journal. 2016;18(10). [In Persian].

Ali Akbari Sichani B. The effect of saffron capsule on cervical ripening for term delivery in primiparous women at Zahra-ye-Marziyeh Hospital in Isfahan City.Thesis for MS Degree in Midwifery Management, Shaheed Beheshti University; 1396. [In Persian].

Mohammadierad R, Mohammad-Alizadeh-Charandabi S, Mirghafourvand M, Fazil F. Effect of saffron with or without date sugar on intensity of pain and anxiety during labor in primiparous females: A randomized, Controlled Trial; 2018. [In Press].

Vallianou N, Gounari P, Skourtis A, Panagos J, Kazazis C. Honey and its anti-inflammatory, anti-bacterial and anti-oxidant properties. Gen Med (Los Angel). 2014;2(132):1-5.

Rahmani R, Khakbazan Z, Yavari P, Granmayeh M, Yavari L. Effect of oral carbohydrate intake on labor progress: randomized controlled trial. Iranian journal of public health. 2012;41(11):59. [In Persian].

Paré J, Pasquier JC, Lewin A, Fraser W, Bureau YA. Reduction of total labor length through the addition of parenteral dextrose solution in induction of labor in nulliparous: Results of dextrons prospective randomized controlled trial. American Journal of Obstetrics and Gynecology. 2017;216(5):5081-87.

Fathi L. The effect of oral honey syrup and date syrup on severity of labor pain and duration of active phase in nulliparous. Thesis for MS Degree in Midwifery Management, Tehran University; 1396. [In Persian].

Qi Z, Kelley E. The WHO traditional medicine strategy 2014-2023: A perspective. Science. 2014;346(6216):S5-S6.

Melnyk JP, Wang S, Marcone MF. Chemical and biological properties of the world's most expensive spice: Saffron. Food Research International. 2010;43(8):1981-9.

Boukraa L. Honey in Traditional and Modern Medicine: CRC Press; 2013.

Kordi M, Nasiri N, Safarian M, Esmaili H, Shadjuo K. The effect of oral honey- date syrup intake during labor on labor progress of nulliparous women. Iranian Journal of Obstetrics, Gynecology and Infertility. 2010;13(2):23-30. [In Persian].

Pazandeh F, Aghakhani S, Dawlatian M, Alavi Majd H. Comparison of the effect of two sectional and continuous oxytocin methods on labor length. SID. 2007;57(16):39-43. [In Persian].