Long Term Effect of COVID-19 on the Brain: Review
Shreerag Devkumar
Datta Meghe Medical College, Nagpur, India.
Rakesh Kumar Jha
Datta Meghe Medical College, Shalinitai Meghe Hospital and Research Centre Nagpur , India.
Dhruba Hari Chandi
Department of Microbiology Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences Sawangi (Meghe), Wardha, India.
*Author to whom correspondence should be addressed.
Abstract
Corona viruses (CoVs) are well-covered RNA viruses that cause enteric and respiratory infections in humans and animals. Many human CoVs have recently gained global interest because of their lethal power and high contagious power. SARS-CoV-2, or COVID-19, is a pathogenic coV that first appeared in Wuhan, China.
Corona virus Disease 2019 (COVID-19) created by SARS-CoV-2, has been declared as pandemic by the World Health Organization since March 11, 2020. The epidemic started in Wuhan and spread rapidly around the world. Corona virus is facing a major epidemic: Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS). SARS-CoV-2 is a virus closely related to SARS.
Corona virus (COVID-19) is caused by SARS-CoV-2 VIRUS, a complex clinical disorder characterized by severe pneumonia and acute respiratory stress syndrome. Serious and neurological disorders, such as encephalitis, coma, fever, epilepsy, and Guillain-Barré syndrome, are more common in cases of COVID-19. In addition, chronic autoimmune and neurodegenerative diseases may occur in SARS-CoV-2 immunopathology and colonization of intestinal and central nervous system, as well as systemic inflammatory response during COVID-19. Parkinson's disease is a common neurodegenerative condition that causes the development of motor and non-motor symptoms.
Keywords: COVID-19, Brain, SARC-CoV-2, Parkinson’s disease and MERS