Clinicopathological Correlation of Germ Cell Tumours in Gonads
V. Lokeshwari
Department of Pathology, Sree Balaji Medical College and Hospital (Affiliated to Bharath Institute of Higher Education and Research’), Chennai, Tamil Nadu, India.
Shanthi Vijayalakshmi
Department of Pathology, Sree Balaji Medical College and Hospital (Affiliated to Bharath Institute of Higher Education and Research’), Chennai, Tamil Nadu, India.
S. Mary Lilly *
Department of Pathology, Sree Balaji Medical College and Hospital (Affiliated to Bharath Institute of Higher Education and Research’), Chennai, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
Ovaries are paired pelvic organs located on thesides of the uterus. Although it is rare in the general population, between the age group of 20-40 years in males,Testicular germ cell neoplasms are the most common form of malignant tumour reported. In young women ovarian tumours rank second among the ovarian germ cell tumors and in males, the testicular germ cell tumorsserves as the leading percentage of tumors among all the testicular tumors seen in the early and late adulthood (3rd and 4th decade) of life. The people of reproductive age group are most vulnerable to gonadal germ cell tumours.Curing this age group without affecting their fertility is a challenging task. The risk of malignancy increases in existence of cryptorchidism/ undescended testis as in our study, 1 case of classical seminoma presented with undescended testis. To study germ cell tumors in gonads in relation to age, parity and mode of presentation and the correlation of biochemical markers and immunohistochemical markers at places in gonadal germ cell tumors.
Keywords: Testicular germ cell neoplasms, ovarian germ cell tumors, gonadal germ cell tumors, malignancy