Study of RBC Histograms and Its Correlation with Etiopathogenesis and Other Parameters in Various Anemias
A. P. Gokula Kannan
Department of Pathology, Sree Balaji Medical College and Hospital (Affiliated to Bharath Institute of Higher Education and Research), Chennai, Tamil Nadu, India.
R. Govindarajan
Department of Pathology, Sree Balaji Medical College and Hospital (Affiliated to Bharath Institute of Higher Education and Research), Chennai, Tamil Nadu, India.
J. Thanka *
Department of Pathology, Sree Balaji Medical College and Hospital (Affiliated to Bharath Institute of Higher Education and Research), Chennai, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
The pluripotent stem cells which are present in the bone marrow renew by its own and differentiate into mature cells. These stem cells undergo division by the presence of erythropoietin, where the nucleus is extruded out from the cell during the end of differentiation, thereby retaining cytoplasmic RNA to form a reticulocyte. The reticulocyte i s a precursor to red blood cell and on losing the RNA it matures into a Red Blood Cell. The present study aimed to analyze the correlation between the automated histogram patterns along with morphological features of RBC‘s prepared from peripheral smear examination in different types of anemia. viz., MCV, MCH, MCHC & RWD- CV.
Keywords: Histograms, etiopathogenesis, MCV, MCH, MCHC