Evaluation of Lympho-vascular Invasion in Breast Carcinoma Using Lymphatic Endothelial Marker (D2-40)
Moumita Dam
Department of Pathology, Sree Balaji Medical College and Hospital, Affiliated to Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Hemalatha Ganapathy
Department of Pathology, Sree Balaji Medical College and Hospital, Affiliated to Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
S. Mary Lilly *
Department of Pathology, Sree Balaji Medical College and Hospital, Affiliated to Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
Breast cancer has become the most frequently diagnosed cancer and the leading cause of cancer-related death among women worldwide, overtaking lung cancer. The Present study attempts to investigate the use of D2 -40 for the detection of lympho- vascular invasion in node negative breast cancer. Additionally the lympho-vascular invasion using D2 -40 and its association with distant metastasis and overall prognosis of the patient was also explored.
Keywords: Vascular invasion, microscopy, LVD, D2-40, prognosis, adenocarcinomas and tumours.