Journal of Pharmaceutical Research International

Objectives: The study was conducted to evaluate the activity of different antibiotics used for various diseases and compare between their different effects among hospitalized patients.

Study Design: Randomized prospected clinical study.

Place and Duration of Study: It was carried out in Al-Zahraa Teaching Hospital and Al-Sader medical city, Iraq/Al-Najaf Town. The present study began at November 2017 and end  at December 2018.                                                       

Methodology:  Sample of 100 patients in Al-Zahraa teaching Hospital and al-Sader Medical City, was randomly collected 90 cases in Al Sader Medical City ( 35 cases of medical ward and 55 cases from Surgical ward). We collected 10 medical condition in Al-Zahra Teaching Hospital from Gynecological and obstetric ward in random manner.

Results: The results of present study reveal a significant difference between ceftriaxone and ceftazidime  and meropenem in treatment intraabdominal operations infection (appendectomy and cholycystectomy) , the results of present study show that 70% of patient used ceftriaxone for treatment of appendectomy and only 30%of patients used ceftazidime for this condition  so there is a significant difference between these two antibiotics (P-value less than 0.05) and only 10% of patients used meropenem (P-value less than 0.02). Other result of present study show significant difference in use meropenem over ceftriaxone in treatment diabetic foot ulcer(60% rate use meropenem over ceftriaxone 40%), in acute kidney injury, there's very high difference in use meropenem 80% versus 10% of vancomycin use (P-value 0.1).

Conclusions: From current study we concluded that the antibiotics used greatly in surgical ward of Hospital followed  by medical ward , in addition to that antibiotics used in postoperation are  more effective than those used in medical ward , so there are a significant differences obtained among antibiotics used in surgical ward.