Bacterial Infections Profile and Patterns for Diabetic Foot Ulcers in Nongovernmental Hospitals of Jordan
Hashem A. Abu-Harirah *
Faculty of Allied medical Sciences- Zarqa University, Jordan.
Ammar Saleem
Faculty of Allied medical Sciences- Zarqa University, Jordan.
Haytham M. Daradka
Department of Medical Laboratory Sciences, Faculty of Pharmacy, Jadara University, Irbid, Jordan.
Ali Ahmad Abu Siyam
Department of Medical Laboratory Sciences, Faculty of Pharmacy, Jadara University, Irbid, Jordan.
Audai Jamal Al Qudah
Islamic hospital, Jordan.
Emad Daabes
Israa hospital, Jordan.
*Author to whom correspondence should be addressed.
Abstract
Background: Many types of infection can cause diabetic foot ulcers Infections involving the bacteria; E. coli, Acinetobacter spp (MDR) and K. pneumoniae, pseudomonas aeruginosa, so the assessment of Bacterial profile and patterns is needed to understand the source and management of these injuries.
Objective: To determine Bacterial infections profile and patterns for diabetic foot ulcers in nongovernmental.
Method: During a period of eleven months, 148 patients with diabetic mellitus foot syndrome (DMFS). Patients were involved, out of 130 which foot ulceration infections. data analysis was done using SPSS version 20. p value was set at <0.05.
Results: Out of 607 Patients with diabetic foot ulceration (DFU) were 130 out of 148 with diabetic mellitus foot syndrome (DMFS). Diabetic foot ulceration (DFU) therefore contributed 20.3% of DMFS among these subjects. Microbiological culture pattern was total of 17 different pathogenic microorganisms were isolated from the participants, one yeast and 16 types of bacteria, from the diabetic foot swabs for ulcers. S. aureus was the most frequent pathogen followed by E.coli then Acinetobacter spp (MDR) and K. pneumonia, then pseudomonas aeruginosa , then p. mirabilis then Streptococcus agalactiae ( group b) then (Enitrobacteria spp and pseudomonas spp and Candida spp and P. vulgaris and K. oxytoca ESBL) then S. viridanse and Enterobacter spp ESBL and Staphylococcus coag. negative). The Enterobacter spp ESBL was the less frequent pathogen.
Conclusion: Diabetic Foot Ulcerations (DFU), is forming about a quarter of the diabetic patient’s tissue infections, the causative agents were bacterial and fungal(yeast). Most of the causative pathogens were; Staphylococcus aureus, and Acinetobacter spp (MDR). The risk of development of High resistant drug isolates of diabetic foot ulcers to be multidrug resistance were high by 53% of total isolated pathogens specially with K. pneumonia (K. pneumoniae), Escherichia coli (E. coli) and Proteus mirabilis bacterial.
Keywords: Diabetic ulcers, foot ulcer, antibiotic susceptibility, Staphylococcus aureus, diabetes, Jordan