Phytochemical Screening and Antifungal Activity of Samadera indica
S. Jaiswal *
Faculty of Pharmacy, Dr. A. P. J. Abdul Kalam University, Dewas Bypass Road Indore, Madhya Pradesh, 452010, India.
R. A. Gupta
Faculty of Pharmacy, Dr. A. P. J. Abdul Kalam University, Dewas Bypass Road Indore, Madhya Pradesh, 452010, India.
*Author to whom correspondence should be addressed.
Abstract
Samadera indica plant is an antifungal and bitter plant spread all over India. The applications of NDDS in phytopharmaceuticals have been widely investigated and various commercial formulations of plants are available in the global market. The goal of nano drug delivery system of herbal extract is to reduce toxicity, to improve drug efficacy, to improve better therapeutic effect, etc. Nanomicelles of samadera indica were successfully prepared by solvent evaporation method and studied various parameters such as Preliminary phytochemical screening, Scanning electron microscopy, and antifungal study. In present methodology, it was concluded that the Nanomicelles of methanolic extract of samadera indica plant was successfully prepared. It was safe and non- toxic. Plant extract contained flavonoids, triterpenes, and alkaloids which is responsible for antifungal activity. This research work concludes that the samadera indica is used as antioxidant, antimicrobial as well as antifungal compound. Novel drug delivery system is a advanced technology for delivering the drug with their so many advantages. Nanomicelles is an excellent pharmaceutical carriers by using bioactive constituents of plant having no side effects, effective formulation for various diseases especially in case of skin diseases. Novel formulation enhanced the topical drug delivery system of Samadera indica in order to treat skin infections was developed.
Keywords: Samadera indica, nanomicelle, fluconazole.