Anti-inflammatory Activity and In silico Approaches on Root Extract of Decalepis hamiltonii Wight & Arn
Palanisamy Prakash
Department Botany, Annamalai University, Annamalai Nagar-608002, Tamil Nadu, India.
Rengarajan Manivasagaperumal *
Department Botany, Annamalai University, Annamalai Nagar-608002, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
Aims: The present study was aimed to evaluate anti-inflammatory and antioxidant potential of methanol root extract of Decalepis hamiltonii.
Results: The methanolic extract showed in vitro anti-inflammatory activity inhibition cells 96.1%µg/ml. MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay was significant inhibited by the methanol (96.2) and inhibition addition the Nitric oxide production 25 µg/ml 95% inhibition. The methanol extract of Decalepis hamiltonii shows a Thus, a very strong approach to In-silico docking and in vitro anti-inflammatory study for whole with these compounds/extract.
Conclusion: From the study it is concluded that the root extract of Decalepis hamiltonii showing a strong approach to In-silico docking and anti inflammatory activity.
Keywords: Decalepis hamiltonii, MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide); nitric oxide, ferric reducing antioxidant power