Pavonia odorata Derived Phytochemicals against Entamoeba histolytica Causing Dysentery
Jogesh Kumar Nayak
Centurion University of Technology and Management, Odisha, India.
Suraj Kumar Sahu
Centurion University of Technology and Management, Odisha, India.
Sitaram Swain
Centurion University of Technology and Management, Odisha, India.
Dipankar Bhattacharyay
Centurion University of Technology and Management, Odisha, India.
Mukundjee Pandey *
Centurion University of Technology and Management, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Phytochemicals from Pavonia odorata plant extract are traditionally used to cure Dysentery. It is caused by Entamoeba histolytica. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that palmitic acid can effectively deactivate the Alcohol dehydrogenase enzyme thereby interrupting the life cycle of the organism.
Keywords: Phytochemical, Pavonia odorata, Entamoeba histolytica