Cinnamomum zeylanicum (Cinnamon) Derived Phytochemicals against Aspartate Semialdehyde Dehydrogenase of Aspergillus fumigatus Causing Aspergillosis
Biswajit Jena
Centurion University of Technology and Management, Odisha, India.
Minati Rani Muni
Centurion University of Technology and Management, Odisha, India.
P. K. Prusty
Centurion University of Technology and Management, Odisha, India.
Sunil Jha
Centurion University of Technology and Management, Odisha, India.
Deepankar Bhatttacharyay *
Centurion University of Technology and Management, Odisha, India and Go to Market Laboratory, Gram Tarang, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Aspergillosis is an infection caused by a type of fungus. The illnesses is caused by aspergillosis infection and usually attack the respiratory system, but their signs and severity vary greatly. It has already been established that plant Cinnamomum zeylanicum belonging to the Lauraceae family has the potential to help controlling aspergillosis. This work is focused on the identification of the particular phytochemical responsible for inhibiting and decreasing the effect of aspergillosis. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that cinnamic acid can effectively deactivate aspergillosis.
Keywords: Phytochemical, Cinnamomum zeylanicum, Aspergillus fumigates